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Specifications
- Antibody Type:Primary
- Antigen Name:Peroxisome Proliferator-Activated Receptor Gamma
- Antigen Symbol:PPARG
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Bovine
- Western Blot:Yes
- Size:200μg
- Environmentally Preferable:
- Gene ID:5468
- Antigen Synonyms:GLM1|PPARG1|PPARG2|PPAR gamma|NR1C3|CIMT1
- Storage Buffer:Preservative: 0.1% Sodium Azide. Constituents: 0.2% Gelatin, PBS
- Storage Temperature:Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
- Concentration:0.2 mg/ml
- Immunogen:The peptide used as the immunogen is contained within the region 410 aa to 460 aa from the human PPARgamma protein.
- Tested Applications:WB
- Purification:Protein A purified
- Cat. No.:89351-480
- Supplier no.:GTX19481
Specifications
About this item
Peroxisome proliferators are non genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements. The PPAR gamma 2 isoform appears to be induced very early in the differentiation of several cultured adipocyte cell lines, and has been suggested to be a dominant regulator of the murine P2 (aP2) gene which encodes an intracellular lipid binding protein which is expressed only in adipose cells. PPAR gamma 2, like several other nuclear hormone receptors, heterodimerizes with RXR alpha.
WB: 1/400. Predicted molecular weight: 58 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: PPARG
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Bovine