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Specifications
- Antibody Type:Primary
- Antigen Name:Angiotensin 1-7
- Antigen Symbol:Ang1-7
- Clonality:Monoclonal
- Clone:C1
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2a kappa
- Reactivity:Multiple
- Western Blot:Yes
- Size:200 µl
- Environmentally Preferable:
- Cross Adsorption:No
- Form:Liquid
- Gene ID:183
- UniProtKB:P01019
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Storage Temperature:Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:BSA conjugated Ang1-7
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MAS085GE2
- Packaging:Vial
Specifications
About this item
Monoclonal Antibody to Angiotensin 1-7 (Ang1-7), derived from BSA conjugated Ang1-7, is reactive with General species.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
- All in stock and fast global delivery
- 100% Quality and service satisfaction guarantee
Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. Astroglia are a plausible cellular target of Ang1-7 in RVLM. Astrocytic responsiveness to Ang1-7 is reduced in SHR. Ang1-7 modulates astrocytic signalling whichin vivo may affect local metabolism and microcirculation, resulting in changes in activity of RVLM pre-sympathetic neurones and hence blood pressure. Ang1-7 is an important component of the central renin-angiotensin system and affects haemodynamics when injected into the RVLM. Effect of Ang1-7 could be blocked by co-application of its antagonist, A779 (200 nM) but not losartan (1 µM). non-CA neurones and glia in RVLM are the primary targets for Ang1-7 and its effect on (Ca²⁺)i in non-CA neurones is enhanced in SHR.
Type: Primary
Antigen: Ang1-7
Clonality: Monoclonal
Clone: C1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: General species