The UVP iBox Studio is sophistication and ease of use in one system for high resolution small animal fluorescence imaging. From in depth in-vivo studies to quick screening, this powerful imaging system can perform any choice of in-vivo application.

• Optimize your application by choosing between two high performance cooled camera options
• Multiple illumination sources – RGBW LEDs and NIR lasers, making the system extremely versatile
• Included warming plate for up to three mice on an ergonomic slide out tray
• Included GFP and RFP emission filters to enable the most common fluorescence applications
• Powerful vision works software allows flexibility of creating custom one-touch workflows or using preinstalled one-touch application templates
• Generates unmodified raw data. Users have the choice of applying image enhancement tools

For researchers with limited focus on, or just starting in vivo pre-clinical studies, it provides highly sensitive fluorescence in vivo imaging at an affordable price. Camera and light source options provide maximum flexibility in system configuration.

It can support imaging of any probe in the visible to near infrared (NIR) range (400 to 900 nm). NIR imaging minimizes skin autofluorescence (~650 nm) and allows 3x to 8x deeper penetration. The wide spectrum also offers more options for multiplex labeling. This capability enables visualization of tissue/tissue interaction, enhanced signal to background ratio, and detection of multiple fluorescent proteins or labels.

Each camera is configured with it to enable rapid in vivo imaging and repeat observation with minimal disturbance to the subject. The included vision works software tools provide users with the freedom to apply image enhancement and analysis features when needed. They create uncompromised raw data and preserve this true data, promising the highest quantitative value. The enhancement and analysis features offered include many powerful tools, such as: colony counting, area density, noise reduction, background subtraction, inversion, pseudocolor, compositing, and more.

Several components are combined in the optional UVP anesthesia system in order to regulate and administer a combination of oxygen and isoflurane/sevoflurane gas to the animal. The initial anesthesia is performed in the induction chamber. The animal is then moved to the warming plate inside the iBox darkroom and connected to a nose cone. The warming plate generates uniform temperature conditions which maintain a safe body temperature of the animal during the imaging process. A low profile breathing device on the plate connects to patented valves. The system’s non-rebreathing technology prevents backflow of gases into the darkroom and ensures user safety.