PAD3 control protein-GST fusion

• Control Protein
• PCA Assays
• ImmunoBlot

PAD3 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. PAD3 modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. It converts arginine to citrulline in filaggrin at a faster rate than it does in trichohyalin (1). Together with the type I enzyme (PAD1), PAD3 play a role in terminal differentiation of the epidermis. PAD3 Protein is ideal for investigators involved in Signaling Proteins, Arginine Deiminase Proteins, and Inflammation Proteins research.

PAD3 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. PAD3 Protein is suitable for use in Western Blot. Expect a band approximately ~97kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.