About this item
This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Type: Primary
Antigen: XRCC6 (p70) & XRCC5 (p80)
Clonality: Monoclonal
Clone: Clone KU729
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Primates
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Specifications
- Catalog No:
- 75956-184
- 75956-186
- Antigen Symbol:
- XRCC6 (p70) & XRCC5 (p80)
- XRCC6 (p70) & XRCC5 (p80)
- Antigen Name:
- Ku-Holo
- Ku-Holo
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 640R
- CF® 640R
- Clone:
- KU729
- KU729
- Reactivity:
- Primates, Human
- Primates, Human
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 292493 (p70); 388739 (p80)
- Unigene ID: 292493 (p70); 388739 (p80)
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage Buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide