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Specifications
- Conjugation:Unconjugated
- Source:
- Species:
- Size:1 mg
- Environmentally Preferable:
- Storage Conditions:–20 °C
- Protein Synonyms:Activity-Dependent Neurotrophic Factor (ADNF) C-AGA-(C8R) HNG1 Peptide|hybrid colivelin Peptide|ADNF-HNG1 Peptide|hybrid Peptide
- Protein/Peptide Name:Colivelin
- Purity:95%
- Molecular Weight:2645.1 Da
- Sequence:SALLRSIPAPAGASRLLLLTGEIDLP
- Cat. No.:103007-098
- Supplier no.:AS-61930
Specifications
About this item
This hybrid peptide named colivelin was synthesized to potentiate the neuroprotective effect of humanin (HN). Colivelin is composed of Activity-Dependent Neurotrophic Factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, a potent HN derivative. Colivelin completely suppresses cell death induced by overexpressed Familial Alzheimer's disease (FAD)-causative genes and beta-amyloid (1-43). Intraperitoneally administered colivelin suppresses memory impairment and might serve as a novel drug candidate for treatment of Alzheimer's disease.
Sequence:SALLRSIPAPAGASRLLLLTGEIDLP
MW:2645.1 Da
% peak area by HPLC:95
Storage condition:-20° C