For In Vitro Diagnostic Use.
This product is intended to be used for immunohistochemical (IHC) procedures. The hydrophobic properties of PAP Pen allow the user to create a barrier on the slides, in any pattern, to confine the flow of reagents to a defined area.
One Mini PAP Pen or one Super PAP Pen

During IHC staining, it is necessary to wipe off the liquid around the sections to reduce dilution of the next reagent applied on the specimen. This is a time-consuming and tedious process. This drawback can be avoided when using PAP pen.

After drying, the circle drawn with the PAP Pen is water-repellent, and alcohol- and acetone-insoluble. The circle provides a barrier to liquids, such as antibody, enzyme, and chromogen solution applied to the sections.

Using PAP Pen can reduce turn around time for staining by eliminating the need for wiping off liquid around sections between different steps of the staining procedure. It reduces the volume of required reagent and it also provides more uniform staining results.

The PAP Pen is well-suited for use on most types of coated and uncoated microscope slides.
Before first time use or when the pen tip is dry:
1. Press tip down against blank glass slide or paper towel to gradually moisten the felt tip with pen’s liquid.
Note: Repeat this step when pen starts to dry out.