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Specifications
- Protein/Peptide Type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage Conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein Synonyms:IL-7|IL7|Interleukin-7
- Protein/Peptide Name:IL7
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular Weight:18.4 kD
- Sequence:Asp26-His177
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:used for biological assays
- Cat. No.:75790-472
- Supplier no.:91-918
Specifications
About this item
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.