About this item
ViraDuctin™ Adenovirus Transduction Reagent is a proprietary reagent designed specifically to increase the efficiency of adenoviral transduction in a variety of cell types, thereby enhancing gene expression studies.
Adenoviral infection of most cells is mediated largely by the coxsackievirus-adenovirus receptor (CAR). In many cells, however, this receptor is either absent or present at extremely low levels, reducing the efficiency of adenovirus uptake. ViraDuctin™ Adenovirus Transduction Reagent increases infection efficiency without regard to the level of CAR expression on the surface of the target cells. It is particularly effective in increasing transduction efficiency in cells expressing CAR at low or non-existent levels, where efficiencies can be increased by as much as 12-fold.
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