Human Recombinant GDF15 (from E. coli)

Supplier: Avantor

Supplier: Avantor

About this item

Recombinant human GDF-15 is lyophilized from a sterile 0.2 μm filtered aqueous solution containing 0.1% trifluoroacetic acid (TFA).

The activity is determined by the inhibition of DU-145 cells and is typically 1 to 2 µg/ml.

Growth and differentiation factor 15 (GDF-15) is a TGFβ family member, made by in the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 is a non-glycosylated, disulfide linked homodimer. It is comprised of two identical 120 amino acid monomers and has a total molecular mass of 26.8 kDa.

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