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Specifications
- Antibody Type:Primary
- Antigen Name:Nuclear Receptor binding SET Domain Protein 1
- Antigen Symbol:NSD1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 647
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Size:100 µL
- Environmentally Preferable:
- Cross Adsorption:No
- Form:liquid
- Gene ID:64324
- Antigen Synonyms:Lysine N-methyltransferase 3B|ARA267|H3-K36-HMTase|H3 lysine-36 and H4 lysine-20 specific|Histone-lysine N-methyltransferase|NSD1|KMT3B|NR-binding SET domain-containing protein|Nuclear receptor-binding SET domain-containing protein 1|H4-K20-HMTase|Androgen receptor-associated protein of 267 kDa|Androgen receptor coactivator 267 kDa protein
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage Temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10478-134
- Supplier no.:BS-8170R-A647
Specifications
About this item
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: NSD1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat