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- Antibody Type:Primary
- Antigen Name:interleukin-1 receptor-associated kinase 1
- Antigen Symbol:IRAK1
- Clonality:Monoclonal
- Clone:8F1A7
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG1
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:0.02 mg
- Environmentally Preferable:
- Cross Adsorption:No
- Form:Liquid
- Gene ID:P51617
- Antigen Synonyms:IRAK1
- Storage Buffer:IRAK Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Temperature:IRAK monoclonal antibody can be stored at –20 °C, stable for one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
- Purification:IRAK Monoclonal Antibody is immunoaffinity chromotography purified IgG.
- Cat. No.:10749-190
- Supplier no.:PM-5317_S
IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kappa B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
Type: Primary
Antigen: IRAK1
Clonality: Monoclonal
Clone: 8F1A7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse