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Specifications
- Antibody Type:Primary
- Antigen Name:Dynamitin
- Antigen Symbol:Dynamitin
- Clonality:Monoclonal
- Clone:2B9A5
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG3
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:150 µL
- Environmentally Preferable:
- Storage Buffer:PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Protein A Purification
- Cat. No.:10086-194
- Supplier no.:60257-1-IG
Specifications
About this item
Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.
Western Blot: Human Brain Tissue, 1:200-1:2000; IHC: Human gliomas Tissue, 1:20-1:200
Type: Primary
Antigen: Dynamitin
Clonality: Monoclonal
Clone: 2B9A5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse