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- Antibody Type:Primary
- Antigen Name:Leukemia Inhibitory Factor Receptor Alpha
- Antigen Symbol:LIFR
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:150 µL
- Environmentally Preferable:
- Antigen Synonyms:SWS|SJS2|CD118|STWS|LIF-R
- Storage Buffer:PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Antigen Affinity Purified
- Cat. No.:10088-230
- Supplier no.:22779-1-AP
LIFR, also known as CD118, is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M . LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway .
Western Blot: Human Skeletal Muscle Tissue, 1:200-1:2000; IHC: Human Skeletal Muscle Tissue, 1:20-1:200
Type: Primary
Antigen: LIFR
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse