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Specifications
- Antibody Type:Primary
- Antigen Name:Transmembrane Protein 106B
- Antigen Symbol:TMEM106B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:150 µL
- Environmentally Preferable:
- Antigen Synonyms:TMEM106B|Transmembrane protein 106B
- Storage Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Antigen affinity Purification
- Cat. No.:10096-074
- Supplier no.:20995-1-AP
Specifications
About this item
TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression. TMEM106B can be showed as 31-40kDa and 60-75kDa (Glycosylated or Dimer) form in western blot test.
Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Brain Tissue, 1:20-1:200
Type: Primary
Antigen: TMEM106B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse