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Specifications
- Antibody Type:Primary
- Antigen Name:paired box 3
- Antigen Symbol:PAX3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:
- Reactivity:Human,Dog,Rat,Mouse
- Western Blot:Yes
- Size:100 ul
- Environmentally Preferable:
- Form:Liquid
- Gene ID:P23760
- Antigen Synonyms:PAX3
- Storage Buffer:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Molecular Weight:53 kDa, 53 kDa, 56 kDa
- Storage Temperature:For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX3 antibody at –20 °C. As with any antibody avoid repeat freeze-thaw cycles.
- Shipping Temperature:4 °C
- Immunogen:Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.
- Purification:Antibody is purified by peptide affinity chromatography method.
- Cat. No.:10100-826
- Supplier no.:27-684
Specifications
About this item
PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2;13) (q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2;13) (q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
PAX3 antibody can be used for detection of PAX3 by ELISA at 1:1562500. PAX3 antibody can be used for detection of PAX3 by western blot at 0.25 ?g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody is purified by peptide affinity chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: PAX3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat, Dog