Anti-CYLD Rabbit Polyclonal Antibody

Catalog # 10346-850

Supplier: Bioss

Catalog # 10346-850

Supplier: Bioss

Supplier Number: BS-2756R

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Specifications

Antibody Type:
Primary
Antigen Name:
Cylindromatosis 1 (turban tumor syndrome)
Antigen Symbol:
CYLD
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western Blot:
Yes
Size:
100 µL
Environmentally Preferable:
Cross Adsorption:
No
Form:
liquid
Gene ID:
1540
Antigen Synonyms:
MFT|EAC|USPL2|CYLD1|BRSS|MFT1|TEM|SBS|CYLDI|CDMT
Storage Buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Storage Temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping Temperature:
4°C
Purification:
Purified by Protein A
Cat. No.:
10346-850
Supplier no.:
BS-2756R

Specifications

About this item

Defects in CYLD are the cause of familial cylindromatosis (CYLD) also known as turban tumor syndrome or dermal eccrine cylindromatosis. CYLD is an autosomal dominant and highly tumor type-specific disorder. The tumors (known as cylindromas because of their characteristic microscopic architecture) are believed to arise from or recapitulate the appearance of the eccrine or apocrine cells of the skin that secrete sweat and scent respectively. Cylindromas arise predominantly in hairy parts of the body with approximately 90% on the head and neck. The development of a confluent mass which may ulcerate or become infected has led to the designation "turban tumor syndrome". The skin tumors show differentiation in the direction of hair structures, hence the synonym trichoepithelioma. CYLD has deubiquitinating activity.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: CYLD
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: