Differentiation kit for the generation of midbrain neuronal precursors from human ES and iPS cell-derived neural progenitor cells.

STEMdiff™ Midbrain Neuron Differentiation Kit is used to generate midbrain neuronal precursors from neural progenitor cells (NPCs) derived from human pluripotent stem cells (hPSCs) using STEMdiff™ SMADi Neural Induction Kit. The midbrain neuronal precursors are further matured into midbrain neurons using STEMdiff™ Midbrain Maturation Kit. These media will produce a population of midbrain neurons (≥15% TH-positive dopaminergic neurons; ≥90% class III βtubulin-positive neurons; <10% GFAP-positive astrocytes). Cells derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.