Specifications
- Antibody type:Primary
- Antigen name:Glutamyl Prolyl tRNA synthetase/ProRS
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:651-750/1512
- Form:Liquid
- Gene ID:2058
- Antigen synonyms:PARS|Cell proliferation-inducing gene 32 protein|Bifunctional aminoacyl-tRNA synthetase|QPRS|QARS|GLNS|GLUPRORS|Glutamatyl-prolyl-tRNA synthetase|EPRS|Bifunctional glutamate/proline--tRNA ligase|PIG32|EARS
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:171 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
Type: Primary
Antigen: Glutamyl Prolyl tRNA synthetase/ProRS
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 651-750/1512
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat