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Anti-Glutamyl Prolyl tRNA synthetase/ProRS Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-Glutamyl Prolyl tRNA synthetase/ProRS Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13393R-A680
Supplier:  Bioss
Anti-Glutamyl Prolyl tRNA synthetase/ProRS Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-13393R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Glutamyl Prolyl tRNA synthetase/ProRS
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Epitope:
    651-750/1512
  • Form:
    Liquid
  • Gene ID:
    2058
  • Antigen synonyms:
    PARS|Cell proliferation-inducing gene 32 protein|Bifunctional aminoacyl-tRNA synthetase|QPRS|QARS|GLNS|GLUPRORS|Glutamatyl-prolyl-tRNA synthetase|EPRS|Bifunctional glutamate/proline--tRNA ligase|PIG32|EARS
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    171 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Type: Primary
Antigen: Glutamyl Prolyl tRNA synthetase/ProRS
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 651-750/1512
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat