- Antibody type:Primary
- Antigen name:FMO3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:
- Western blot:Yes
- Environmentally Preferable:
- Epitope:111-210/532
- Form:Liquid
- Gene ID:2328
- Antigen synonyms:FMO3_HUMAN|FMO II|Hepatic flavin containing monooxygenase 3|dJ127D3.1|FMO form 2|FMO 3|Dimethylaniline oxidase 3|Hepatic flavin-containing monooxygenase 3|FMOII|FMO3|Trimethylamine monooxygenase|Flavin containing monooxygenase 3|MGC34400|Dimethylaniline monooxygenase 3|Dimethylaniline monooxygenase [N oxide forming] 3|TMAU|Dimethylaniline monooxygenase [N-oxide-forming] 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:60 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human FMO3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.
Type: Primary
Antigen: FMO3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 111-210/532
Host: Rabbit
Isotype: IgG
Reactivity: