- Antibody type:Primary
- Antigen name:E Cadherin Ser838 + Ser840
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:
- Environmentally Preferable:
- Form:Liquid
- Gene ID:999
- Antigen synonyms:anion exchanger protein 3|Uvomorulin|CD324|cadherin 1 type 1 E-cadherin|epithelial calcium dependant adhesion protein|ECAD|CD324 antigen|Epithelial cadherin|CAM 120/80|Arc 1|Cadherin1|CADH1_HUMAN|Liver cell adhesion molecule|Cadherin 1|CD 234|p-E Cadherin phospho S838 + S840|LCAM|E Cadherin phospho S838 + S840|E-cadherin|CDH1|CDHE|UVO
- Modification:Phosphorylation (Ser838+Ser840)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:90/97 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human E Cadherin around the phosphorylation site of Ser838+Ser840
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Cadherins comprise a family of Ca²⁺-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterised by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function.
Type: Primary
Antigen: E Cadherin Ser838 + Ser840
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: