- Antibody type:Primary
- Antigen name:ADH5
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Environmentally Preferable:
- Epitope:301-374/374
- Form:Liquid
- Gene ID:128
- Antigen synonyms:Glutathione dependent formaldehyde dehydrogenase|FDH|ADHX_HUMAN|GSH-FDH|Alcohol dehydrogenase class chi chain|Alcohol dehydrogenase class 3|Alcohol dehydrogenase class III chi polypeptide|Alcohol dehydrogenase class-3|class III alcohol dehydrogenase 5 chi subunit|hydroxymethyllutathione dehydrogenase|Glutathione-dependent formaldehyde dehydrogenase|alcohol dehydrogenase 5 class III chi polypeptide|Alcohol dehydrogenase class III|formaldehyde dehydrogenase|FALDH|S-hydroxymethylglutathione dehydrogenase|Alcohol dehydrogenase 5|ADH5|Alcohol dehydrogenase class-III|ADHX|ADH 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:40 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ADH5
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Type: Primary
Antigen: ADH5
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 301-374/374
Host: Rabbit
Isotype: IgG
Reactivity: Mouse