Anti-CAP Rabbit Polyclonal Antibody (Alexa Fluor® 750)
BOSSBS-9759R-A750
: Bioss
- Antibody type:Primary
- Antigen name:CAP
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:65-160/1362
- Form:Liquid
- Gene ID:23476
- Antigen synonyms:bromodomain containing protein 4|Bromodomain-containing protein 4|Brd4|Protein HUNK1|HUNK1|BRD4_HUMAN|CAP|chromosome associated protein
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Brd4/CAP
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.
Type: Primary
Antigen: CAP
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 65-160/1362
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat