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Anti-A Raf Ser299 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-A Raf Ser299 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3371R-A750
Supplier:  Bioss
Anti-A Raf Ser299 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3371R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    A Raf Ser299
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Form:
    Liquid
  • Gene ID:
    369
  • Antigen synonyms:
    ARaf proto oncogene serine/threonine protein kinase|A Raf proto oncogene serine/threonine protein kinase|ARAF1|A raf 1|PKS|Oncogene PKS2|RAFA 1|v raf murine sarcoma 3611 viral oncogene homolog|RAFA1|ARAF_HUMAN|PKS2|ARAF 1|v raf oncogene homolog 1 murine sarcoma 3611 virus|A RAF phospho S299|PKS 2|ARAF|v raf murine sarcoma 3611 viral oncogene homolog 1|Oncogene Araf1|Ras binding protein DA Raf|Proto oncogene Pks|p-A RAF phospho S299
  • Modification:
    Phosphorylation (Ser299)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    67 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human A Raf around the phosphorylation site of Ser299
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.

Type: Primary
Antigen: A Raf Ser299
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human