Anti-A Raf Ser299 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3371R-A750
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:A Raf Ser299
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Form:Liquid
- Gene ID:369
- Antigen synonyms:ARaf proto oncogene serine/threonine protein kinase|A Raf proto oncogene serine/threonine protein kinase|ARAF1|A raf 1|PKS|Oncogene PKS2|RAFA 1|v raf murine sarcoma 3611 viral oncogene homolog|RAFA1|ARAF_HUMAN|PKS2|ARAF 1|v raf oncogene homolog 1 murine sarcoma 3611 virus|A RAF phospho S299|PKS 2|ARAF|v raf murine sarcoma 3611 viral oncogene homolog 1|Oncogene Araf1|Ras binding protein DA Raf|Proto oncogene Pks|p-A RAF phospho S299
- Modification:Phosphorylation (Ser299)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:67 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human A Raf around the phosphorylation site of Ser299
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
Type: Primary
Antigen: A Raf Ser299
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human