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Anti-NLRP3 Mouse Monoclonal Antibody [clone: Cryo-1]
Anti-NLRP3 Mouse Monoclonal Antibody [clone: Cryo-1]
Catalog # PRSI36-099
Supplier:  ProSci Inc.
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Anti-NLRP3 Mouse Monoclonal Antibody [clone: Cryo-1]
Catalog # PRSI36-099
Supplier:  ProSci Inc.

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    NLR Family, pyrin Domain Containing 3
  • Antigen symbol:
    NLRP3
  • Clonality:
    Monoclonal
  • Clone:
    Cryo-1
  • Conjugation:
    Unconjugated
  • Host:
    Mouse
  • Isotype:
    IgG2b
  • Reactivity:
    Mouse
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Form:
    Liquid
  • Gene ID:
    216799
  • Antigen synonyms:
    MWS|AII|LRR and PYD domains-containing protein 3|FCU|AGTAVPRL|cryopyrin|NACHT|and PYD-containing protein 3|NALP3|cold autoinflammatory syndrome 1 protein|C1orf7|CLR1.1|AVP|leucine-rich repeat-|CIAS1|nucleotide-binding oligomerization domain|FCAS|PYRIN-containing APAF1-like protein 1|leucine rich repeat and pyrin domain containing 3|PYPAF1|caterpiller protein 1.1|LRR and PYD containing protein 3|NACHT domain-
  • Storage buffer:
    In PBS containing 10% glycerol and 0.02% sodium azide.
  • Storage temperature:
    Stable for at least 1 year after receipt when stored at -20˚C.
  • Concentration:
    1 mg/ml
  • Shipping temperature:
    -20°C
  • Immunogen:
    Recombinant mouse NLRP3/NALP3 (pyrin domain/aa 1-93).
  • Purification:
    >95% (SDS-PAGE)
  • Size:
    100 μg
  • Pk:
    100 µG

Specifications

About this item

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).

Type: Primary
Antigen: NLRP3
Clonality: Monoclonal
Clone: Cryo-1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Mouse