Specifications
- Antigen symbol:IRF2BP2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:IRF2BP2 antibody was raised against an 17 amino acid synthetic peptide near the amino terminus of human IRF2BP2.
- Tested applications:E, IHC
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
Specifications
About this item
IRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.
Type:
Antigen: IRF2BP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human