Specifications
- Antigen name:Caspase Recruitment Domain Family, Member 10
- Antigen symbol:CARD10
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:Carma 3|CARD-containing MAGUK protein 3|CARMA3|BIMP1|Caspase recruitment domain-containing protein 10
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.
- Tested applications:E, WB, ICC, IF
- Purification:Immunoaffinity purified
- Size:100 µg
- Pk:100 µG
Specifications
About this item
CARD10 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kappa B. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the I kappa K complex, demonstrating its importance in the regulation of NF-kappa B transcription factor activation.
Type:
Antigen: CARD10
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse