- Antibody type:Primary
- Antigen name:Chitinase 3-like 1
- Antigen symbol:CHI3L1
- Clonality:Polyclonal
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:1116
- Antigen synonyms:CGP-39|GP-39|YYL-40|GP39|YKL40|HCGP-3P|YKL-40|HC-gp39|hCGP-39|Cartilage glycoprotein-39|ASRT7
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:370-381/383
- Purification:Purified by Protein A
- Pk:100 µl
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
Recommended Dilutions: Flow Cytometry: 1:20-100
Type: Primary
Antigen: CHI3L1
Clonality: Polyclonal
Clone:
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rabbit
Isotype:
Reactivity: