- Antibody type:Primary
- Antigen name:Calcium channel, Voltage-dependent, T type alpha 1G And 1H Subunit
- Antigen symbol:CACNA1G + CACNA1H
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 350
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:CAC1G_HUMAN|Voltage gated calcium channel subunit alpha Cav3.1|Voltage gated calcium channel subunit alpha Cav3.2|Cav3.1c|Voltage dependent T type calcium channel subunit alpha 1H|CAC1H_HUMAN.|Voltage dependent T type calcium channel subunit alpha 1G|Low voltage activated calcium channel alpha1 3.2 subunit|NBR13
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. There are 2 isoforms of CACNA1H and 14 isoforms if CACNA1G, produced by alternative splicing.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CACNA1G + CACNA1H
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat