Specifications
- Antibody type:Primary
- Antigen name:Protein Tyrosine Phosphatase, Receptor Type, R
- Antigen symbol:PTPRR
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 350
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Protein-tyrosine phosphatase PCPTP1|Protein tyrosine phosphatase receptor type R|Ch-1PTPase|ECPTP|PTPSL|PTP SL|Ch1 PTPase|Protein tyrosine phosphatase NC PTPCOM1|NC PTPCOM1|PTPRR_HUMAN|NC-PTPCOM1|Protein tyrosine phosphatase PCPTP1|PTPRQ|PTPRR|DKFZp781C1038|Protein tyrosine phosphatase Cr1PTPase precursor|Receptor type tyrosine protein phosphatase R|Receptor-type tyrosine-protein phosphatase R.|R-PTP-R|EC PTP|PTPBR7
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localized to the cell membrane, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm.
Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200
Type: Primary
Antigen: PTPRR
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat