Anti-MUC5AC Mouse Monoclonal Antibody [clone: MUC5AC/917 45M1]

Mucin 5AC glycoprotein (MUC5AC) is a 641 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Purified

Type: Primary
Antigen: MUC5AC
Clonality: Monoclonal
Clone: MUC5AC/917 45M1
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human

Catalog No:
BNUB1134-100
BNUB1134-500

Antigen symbol:
MUC5AC
MUC5AC

Antigen name:
Mucin 5AC
Mucin 5AC

Antigen synonyms:
Mucin 5AC oligomeric mucus/gel forming|Mucin 5 Subtypes A And C|Apomucin Major Airway Glycoprotein|Tracheobronchial Mucin (TBM)|Mucin 5 subtype AC tracheobronchial
Mucin 5AC oligomeric mucus/gel forming|Mucin 5 Subtypes A And C|Apomucin Major Airway Glycoprotein|Tracheobronchial Mucin (TBM)|Mucin 5 subtype AC tracheobronchial