Anti-NKX2-2 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: NX2/294]
Catalog # BNUM0294-50
Supplier: Biotium
Specifications
- Antibody type:Primary
- Antigen name:NK2 homeobox 2
- Antigen symbol:NKX2-2
- Clonality:Monoclonal
- Clone:Clone NX2/294
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG2b kappa
- Reactivity:Chicken,Human,Rat,Mouse
- Environmentally Preferable:
- Gene ID:516922
- Antigen synonyms:NK2 transcription factor like protein B|NKX22|NK2 transcription factor related locus 2|Nkx2b|tinman|Homeobox protein NK-2 homolog B
- Storage buffer:PBS/0,05% azide
- Concentration:1 mg/mL
- Purification:BSA-free
- Size:50 μL
- Pk:50 µl
Specifications
About this item
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Type: Primary
Antigen: NKX2-2
Clonality: Monoclonal
Clone: NX2/294
Conjugation: Purified, BSA-free
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Chicken, Human, Mouse, Rat