About this item
Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Type: Primary
Antigen: BAX
Clonality: Monoclonal
Clone: 2D2
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Monkey
Specifications
- Catalog No:
- BNCB0004-100
- BNCB0004-500
- Antigen symbol:
- BAX
- BAX
- Antigen name:
- Bax
- Bax
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Biotin
- Biotin
- Clone:
- Clone 2D2
- Clone 2D2
- Reactivity:
- Monkey, Human
- Monkey, Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 624291
- 624291
- Isotype:
- IgG1
- IgG1
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: KIMBERLY CLARK
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: Merck
Supplier: VWR Collection
Supplier: VWR Collection