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Anti-METTL11A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-METTL11A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-6057R-A750
Supplier:  Bioss
Anti-METTL11A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-6057R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    METTL11A
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat,
    Mouse
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Epitope:
    25-130/223
  • Form:
    Liquid
  • Gene ID:
    28989
  • Antigen synonyms:
    HOMT1A|NRMT|N-terminal Xaa-Pro-Lys N-methyltransferase 1|Methyltransferase-like protein 11A|Alpha N-terminal protein methyltransferase 1A|X-Pro-Lys N-terminal protein methyltransferase 1A|NTM1A|NTMT1|AD-003|NRMT1|N-terminal RCC1 methyltransferase|METTL11A|C9orf32
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    25 kDa
  • Storage temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human METTL11A
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.

Type: Primary
Antigen: METTL11A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 25-130/223
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat

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