Specifications
- Antibody type:Primary
- Antigen name:UGT2B4
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:
- Western blot:Yes
- Environmentally Preferable:
- Epitope:111-210/528
- Form:Liquid
- Gene ID:7363
- Antigen synonyms:UDP glucuronosyltransferase 2B4 precursor|UD2B4_HUMAN|UGT2B11|UDP glycosyltransferase 2 family polypeptide B4|UDPGTh 1|UDP glucuronosyltransferase 2 family polypeptide B4|UDP glycosyltransferase|UDP glucuronyltransferase family 2 beta 4|UDPGTh1|Hyodeoxycholic acid|UDPGT|HLUG25|UGT2B4
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:58 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human UGT2B4
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholoestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.
Type: Primary
Antigen: UGT2B4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 111-210/528
Host: Rabbit
Isotype: IgG
Reactivity: