Specifications
- Antigen name:Death Receptor 3
- Antigen symbol:DR3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Antigen synonyms:DR3|LARD|Tumor necrosis Factor Receptor superfamily member 25|RP4-650H14.2|WSL-LR|TR3|WSL-1|APO-3|TNFRSF12|DDR3|TRAMP
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:DR3 antibody was raised against a peptide corresponding to amino acids in extracellular domain of human DR3 precusor.
- Tested applications:E, WB, ICC, IF
- Purification:DEAE purified
- Size:100 µg
- Pk:100 µG
Specifications
About this item
DR3 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappa B activation.
Type:
Antigen: DR3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse