Specifications
- Antibody type:Primary
- Antigen name:Catenin Delta 2
- Antigen symbol:CTNND2
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 350
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:GT24|CTND2_HUMAN|Neural plakophilin related arm repeat protein|Delta catenin|Catenin Cadherin associated protein delta 2|CTNND2|Neurojungin|Catenin delta 2|NPRAP|CTNND 2|Catenin delta-2|Neural plakophilin related armadillo repeat protein|Delta-catenin|GT 24|Neural plakophilin-related ARM-repeat protein
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CTNND2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype:
Reactivity: