Specifications
- Antibody type:Primary
- Antigen name:Protein kinase C type alpha and beta
- Antigen symbol:PRKCA + PRKCB
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Cross adsorption:No
- Form:Liquid
- Gene ID:282323
- Antigen synonyms:Protein kinase C beta type|PKC-A|PRKACA|PKC-B|Protein kinase C alpha type|PRKC Pan|PKC-alpha|PRKCA|PKC-beta|PKCB|PRKCB1|PKCA
- Storage buffer:Aqueous buffered solution containing 100 μg/ml BSA, 50% glycerol and 0,09% sodium azide. Store at –20 °C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4 °C
- Immunogen:5-55/351
- Purification:Purified by Protein A
- Size:100 μl
- Pk:100 µl
Specifications
About this item
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalised pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).
Recommended dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: PRKCA + PRKCB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat