PRP-1 polymeric HPLC columns are designed for broad ranging uses, similar to C8 or C18 HPLC materials. They combine the best characteristics of silica-based and polymeric columns resulting in highly inert and long-lasting columns. These columns are ideal for applications that require a high degree of column to column and batch to batch consistency (quality assurance, clinical trials). Unlike C8 or C18 columns, PRP-1 has no stationary phase coating. Since there is no stationary phase to hydrolyse, the column maintains its performance characteristics longer than many C8 or C18 columns.

• Made entirely of polystyrene-divinylbenzene, there are no silanol groups to cause sample loss
• Cross-linked to prevent shrinkage or swelling

Quality assurance as well as research and development laboratories find that PRP-1 columns last significantly longer than silica-based C8 or C18 columns. This is particularly true for difficult analyses such as high pH samples (pH 8-13), labile or reactive samples (irreversible adsorption), high aqueous purifications (80-100% water), and separations with ion pairing reagents.