Bio-compatible adhesive to seal live tissues. Ideal for neuroscience applications, nerve studies and more.

• Embed peripheral nerves with electrodes
• Pre-mixing tips simplify use (Includes 10 mixing tips)
• Medium strength adhesion
• Low toxicity
• Rapid curing silicone adhesive, cure on contact
• Cures without producing heat

Kwik-Cast™ is a very low viscosity silicone sealant developed to embed peripheral nerves with electrodes for acute multi-fiber recordings. It flows easily, filling the small spaces around the nerve and leaving no channels through which peritoneal fluid can travel and thus short the nerve/electrode contact. Equally important is the ability of the material to flow into itself and create one continuous mass from underneath the nerve all the way to the top of the nerve/electrode contact to ensure long-term recording stability.

Kwik-Cast is color-coded to make the mixing foolproof. The catalyst is yellow and the base is blue. When uniformly mixed, it is green. Kwik-Cast can be applied and cured underneath mineral oil. After recording, electrodes are easily recovered due to the low tear strength. The slight longer curing time (approx. 3 minutes) makes it more suitable for stationary preparations and in vitro tissue studies.

Kwik-Cast silicones have very low toxicity before, during and after curing. The by-product of curing is a small amount of hydrogen gas, which is much less toxic to cells than acetic acid or alcohol from traditional RTV silicone systems.

The curing speed is hundreds of times faster than traditional RTV silicones. A curing time of a few minutes at room temperature is especially useful for encapsulation of live tissue or implanting into a live animal. Unlike many vinyl-based silicones in which the platinum complex catalysts are easily poisoned by contamination from amines and animal tissue, Kwik-Sil and Kwik-Cast are not sensitive to contamination from animal tissue.