About this item
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Type: Primary
Antigen: NCAM1
Clonality: Monoclonal
Clone: Clone 123A8 (same as 56C04)
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75914-546
- 75914-548
- Antigen Symbol:
- NCAM1
- NCAM1
- Antigen Name:
- CD56 / NCAM
- CD56 / NCAM
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 568
- CF® 568
- Clone:
- 123A8 (same as 56C04)
- 123A8 (same as 56C04)
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 503878
- Unigene ID: 503878
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage Buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide