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- Antibody Type:Primary
- Antigen Name:MUC5AC Clone Nd-2
- Clonality:Monoclonal
- Clone:Nd-2
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Size:7 mL
- Environmentally Preferable:
- Form:Liquid
- Storage Temperature:+4 °C
- Shipping Temperature:4°C
- Purification:Purified by precipitation
- Cat. No.:75815-266
- Supplier no.:60-0160-7
For In Vitro Diagnostic Use.
This product is used to qualitatively detect MUC5AC in normal and neoplastic formalin fixed, paraffin embedded (FFPE) tissue sections in immunohistochemical (IHC) detection methodology. Interpretation must be made within the context of the patient’s clinical history and other diagnostic test by a qualified pathologist.
Mucins are high molecular weight glycoproteins which produced by epithelial cells and constitute the major component of the mucus layer that protects the gastric epithelium from chemical and mechanical aggressions. Mucins can be divided into two families; secretory mucins and membrane bound mucins. Mucin MUC5AC is a secretory mucin. MUC5AC is not expressed in normal pancreas but is expressed by most pancreatic ductal adenocarcinomas. MUC5AC is expressed also by endocervical adenocarcinomas and a variable number of tumors of the gastrointestinal tract. Together with a panel of antibodies, antibodies to MUC5AC may be useful for identification of pancreatic carcinoma and pre-cancerous changes and differentiation of intestinal metaplasia.
This antibody is diluted in 10 mM Phosphate buffered saline (PBS), pH 7.2 containing 1% bovine serum albumin (BSA) and 0.09% sodium azide (NaN3) as antimicrobial agent.
For professional users.
Proper handling of this product as with any product derived from biological sources according to local and applicable regulations.
Sodium azide is a toxic chemical. The concentration in this product is not classified as hazardous; however, the build-ups of NaN3 may react with lead and copper plumbing to form highly explosive metal azides. Flush the disposed reagent with large volume of water to prevent azide build-up.
60-0160-7: Ready-To-Use
61-0160; 61-0160-2; 61-0160-5: Dilute 1:100 to 1:200 before use when using Power-StainTM and Acu-StainTM detection systems. Optimum dilution factor may vary depending on the specimen and preparation process and should be determined by each individual investigator.
Incubate this antibody with tissue section for 30-60 minutes at room temperature. Follow the instructions from the selected detection system.
Positive Control: Stomach
Antigen Retrieval: Proteinase K
Staining Pattern: Cytoplasm and perinuclear
Type: Primary
Antigen: MUC5AC Clone Nd-2
Clonality: Monoclonal
Clone: Nd-2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human