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Specifications
- Antibody Type:Primary
- Antigen Name:DENN domain-containing protein 1B
- Antigen Symbol:DENND1B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:
- Reactivity:Human
- Western Blot:Yes
- Size:400 ul
- Environmentally Preferable:
- Epitope:Amino Acid Range = 39-68
- Form:Liquid
- Gene ID:Q6P3S1
- Antigen Synonyms:DENND1B
- Modification:None
- Storage Buffer:Supplied in PBS with 0.09% (W/V) sodium azide.
- Molecular Weight:48 kDa
- Storage Temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0.5 mg/mL
- Shipping Temperature:4 °C
- Immunogen:This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Cat. No.:76009-382
Specifications
About this item
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
For WB starting dilution is: 1:500 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Type: Primary
Antigen: DENND1B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human