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Specifications
- Antibody Type:Primary
- Antigen Name:Carnitine Palmitoyltransferase 1C
- Antigen Symbol:CPT1C
- Clonality:Polyclonal
- Conjugation:Cy3®
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Size:100 µL
- Environmentally Preferable:
- Cross Adsorption:No
- Form:liquid
- Gene ID:126129
- Antigen Synonyms:carnitine acyltransferase-like protein 1|FLJ23809|CPTIC|CATL1|CPT1P|CPT1-like pseudogene|carnitine palmitoyltransferase 1C|CPT1C|carnitine palmitoyltransferase I related C
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage Temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10255-256
- Supplier no.:BS-11416R-CY3
Specifications
About this item
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CPT1C
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype:
Reactivity: