Specifications

• Antibody Type:
  Primary
• Antigen Name:
  Zic Family member 1
• Antigen Symbol:
  ZIC1
• Clonality:
  Monoclonal
• Clone:
  1D12
• Conjugation:
  Unconjugated
• ELISA:
  Yes
• Host:
  Mouse
• Isotype:
• Reactivity:
  Human
• Western Blot:
  Yes
• Size:
  100 µg
• Environmentally Preferable:
• Cross Adsorption:
  No
• Gene ID:
  7545
• Antigen Synonyms:
  Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is a gene critical to cerebellar pattern formation. The expression of Zic genes is first detected at gastrulation and at neurulation|becoming restricted to the dorsal neural ectoderm and the dorsal paraxial mesoderm. The Zic1 gene has been mapped to chromosome 9 in mouse. The 5' flanking region of the Zic1 gene contains a region-specific enhancer determined to be essential in in-vivo and in-vitro deletion analysis. The temporal profile of mRNA expression differs for each of the Zic gene products. The Drosophila odd-paired gene is highly homologous to the Zic gene family. Zic2 and Zic3 are highly similar genes. Zic2 is essential for the formation of the brain and Zic-3 is important for right and left axis formation.
• Storage Temperature:
  Cool
• Shipping Temperature:
  Ice
• Cat. No.:
  10606-146
• Supplier no.:
  H00007545-M04