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Specifications
- Antibody Type:Primary
- Antigen Name:AKT1 substrate 1 (proline-rich)
- Antigen Symbol:AKT1S1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Environmentally Preferable:
- Form:Liquid
- Gene ID:Q96B36
- Antigen Synonyms:AKT1S1
- Storage Buffer:AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular Weight:Predicted: 30 kDa Observed: 28 kDa
- Storage Temperature:AKT1S1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:AKT1S1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1. The immunogen is located within amino acids 190 - 240 of AKT1S1.
- Purification:AKT1S1 Antibody is affinity chromatography purified via peptide column.
- Cat. No.:10062-560
- Supplier no.:7391
Specifications
About this item
AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
AKT1S1 antibody can be used for detection of AKT1S1 by Western blot at 1 - 2 ?g/mL.
AKT1S1 Antibody is affinity chromatography purified via peptide column.
AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: AKT1S1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat