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Specifications
- Antibody Type:Primary
- Antigen Name:CD209 molecule
- Antigen Symbol:CD209
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:0.1 mg
- Environmentally Preferable:
- Form:Liquid
- Gene ID:Q9NNX6
- Antigen Synonyms:CD209
- Storage Buffer:DC-SIGN Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular Weight:Predicted: 44 kDa Observed: 47 kDa
- Storage Temperature:DC-SIGN antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:DC-SIGN antibody was raised against a synthetic peptide corresponding to 21 amino acids near the center of human DC-DIGN. The immunogen is located within the last 50 amino acids of DC-SIGN.
- Tested Applications:E, WB, IHC, IF
- Purification:DC-SIGN Antibody is affinity chromatography purified via peptide column.
- Cat. No.:89415-448
- Supplier no.:2347
Specifications
About this item
DC-SIGN Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
Type: Primary
Antigen: CD209
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human