CAS Number: 50-01-1
MDL Number: MFCD00013026
Molecular Formula: CH5N3
Molecular Weight: 95.53
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 186

Expand 2 Items

Guanidinium hydrochloride ≥99%, white crystalline powder, Ultrapure

Supplier: MP Biomedicals

Guanidine Hydrochloride is a protein denaturant and thus having an important role in molecular weight determinations.
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase. Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins. It apparently disrupts hydrogen bonds which hold the protein in its unique structure. However, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions.

Expand 3 Items

Guanidinium hydrochloride 99.5%, anti-caking agent_without

Supplier: Thermo Scientific Chemicals

Guanidinium hydrochloride 99.5%, anti-caking agent_without

Expand 2 Items

Guanidinium hydrochloride 98%

Supplier: Thermo Scientific Chemicals

Guanidinium hydrochloride 98%

Expand 3 Items

Guanidinium hydrochloride ≥99%, white crystalline powder Optical Density Grade

Supplier: MP Biomedicals

Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.

Expand 3 Items

Guanidinium hydrochloride 99,0 for synthesis

Supplier: TCI America

[for Protein Research]
CAS Number: 50-01-1
MDL Number: MFCD00013026
Molecular Formula: CH5N3
Molecular Weight: 95.53
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 187

Expand 3 Items

Guanidinium hydrochloride, white powder, Practical grade

Supplier: MP Biomedicals

Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.

Expand 3 Items

Guanidinium hydrochloride 99, powder_crystalline, ultrapure

Supplier: MP Biomedicals

Applications
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. It is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA.
Product Description
The crystal structure of Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds,it is a strong chaotropic agent.Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a freeflowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical

Grade: Ultra Pure
Purity: >99%
Keywords: Guanidium chloride, chaotropic agent
Key Applications: Chaeotropic agent
Product Type: Biochemicals
Biochemical Category: Chaotropic Agents
Density: 1.345 g/cm³ at 20 °C (Lit.)
Melting Point: 180-190 °C
UV/Visible Absorbance: OD260nm (6.0 M aq soln) <0.03
Presentation: White Crystalline Powder
pH: 4-6 (6.0 M aq soln)
Solubility: Soluble in water,Clear, Colorless Solution (6 M - clear, colorless solution).
Storage & Handling: Room Temperature, desiccate

Expand 5 Items

Guanidinium hydrochloride Molecular_Biology, Millipore®

Supplier: MilliporeSigma

Guanidinium hydrochloride Molecular_Biology, Millipore®

Expand 2 Items

Guanidinium hydrochloride

Supplier: MilliporeSigma

Guanidinium hydrochloride

Expand 2 Items

Guanidinium hydrochloride ≥99.5%, OmniPur®, Calbiochem®, Millipore®

Supplier: MilliporeSigma

For molecular biology. DNase-, RNase-, protease-, and phosphatase-free.

Expand 3 Items

Guanidinium hydrochloride 99 Titrimetric, ULTROL®, Calbiochem®

Supplier: MilliporeSigma

Powerful protein denaturant.

Expand 3 Items

Guanidinium hydrochloride 99, BiotechGrade excipient_suitable, Biochemistry

Supplier: Spectrum Chemicals

Guanidine Hydrochloride, BiotechGrade is considered a chaotrope and a strong denaturants utilized in physiochemical studies of protein folding. Proteins become randomly coiled at high concentrations of guanidinium chloride. Spectrum offers highly pure reagents suitable for biochemical research and analysis. The critical parameters involved are absence of inhibitors such as traces of heavy metals as well as biochemical function tests for enzymes, coenzymes and enzyme substrates.

Expand 4 Items

Guanidinium hydrochloride 99, powder_white crystalline Molecular_Biology

Supplier: MP Biomedicals

Storage: Room Temperature
Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical.
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. Guanidine hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins.

Expand 5 Items

Guanidinium hydrochloride 98

Supplier: BeanTown Chemical

CAS: 50-01-1; EC No: 200-002-3; MDL No: MFCD00013026; RTECS: MF4300000 Crystalline; Molecular Formula: CH5N3·HCl; MW: 95.53 Melting Point: 180-185° Density (g/mL): 1.344 Hygroscopic

Expand 3 Items

Guanidinium hydrochloride 99,5 Molecular_Biology

Supplier: Promega Corporation

Guanidine-HCl, Molecular Grade, is commonly used for the isolation of intact mRNA from tissues or cultured cells.

Expand 2 Items

Guanidinium hydrochloride 8 mol/l in aqueous solution

Supplier: G-Biosciences

A selection of strong chemicals to aid in the denaturation of proteins. Denaturants, or chaotropes, disrupt water interactions resulting in the solubilization of hydrophobic proteins and peptides. The chaotropes also act on all proteins to unfold them and alter their three-dimensional structure.