- Antibody type:Primary
- Antigen name:Tumor protein p53
- Antigen symbol:P53
- Clonality:Polyclonal
- Conjugation:Cy5®
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:7157
- Antigen synonyms:or transformation-related protein 53 (TRP53)|tumor suppressor p53|antigen NY-CO-13|P53|BCC7|TRP53|phosphoprotein p53|LFS1|tumor protein p53
- Modification:phospho-Thr55
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: P53
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human