Anti-MARCH9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog # BOSSBS-9343R-A680

Supplier: Bioss

Catalog # BOSSBS-9343R-A680

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
MARCH9
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 680
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Epitope:
201-300/346
Form:
Liquid
Gene ID:
92979
Antigen synonyms:
Membrane associated RING finger protein 9|MARCH IX|MARH9_HUMAN|membrane associated ring finger C3HC4 9|RING finger protein 179|Membrane associated RING CH protein IX|RNF179|E3 ubiquitin protein ligase MARCH9
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Storage temperature:
Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human MARCH9
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localises to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

Type: Primary
Antigen: MARCH9
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-300/346
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat